Genes of unknown function in a minimal cell
Assign biological function to the genes of the minimal synthetic cell JCVI-syn3A that are still uncharacterised, several of which are essential for growth.
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Open problems
Each problem states how progress is verified and what counts as a contribution. Besides the problems curated here, the catalogue includes open conjectures from Formal Conjectures (with Lean statements), optimization constants and the AlphaEvolve problems. Know one that belongs here? Propose a problem.
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